Posted in Flagyl on December 19, 2015

I unceremoniously experienced my first case of C. diff during the first of my two, modified autologous progeny cell transplants this summer. All I knew is everyone wore golden paper gowns when they came in and through of my room–and I needed to hap an IV pole with me in the manner that I sprinted the six steps to the bathroom every hour.

I was treated by IV antibiotics and certified “C. diff free” moiety way through my stay; one of the reasons I was yanked back similar to an outpatient and kept up up~ the body the 7th floor in the BMT unit for the last couple of weeks.

No issues through it during my second transplant. But not to worry: I fought a encourage, for me more painful stomach poison during that stay.

So what is C. diff? Here’s a fast blurb I borrowed from Mayo Clinic’s website:

Clostridium difficile (klos-TRID-e-um dif-uh-SEEL), frequently called C. difficile or C. diff, is a bacterium that have power to cause symptoms ranging from diarrhea to life-threatening inflammation of the colon.

Illness from C. difficile most commonly affects older adults in hospitals or in diffuse-term care facilities and typically occurs ~wards use of antibiotic medications.

It does move on to say that C. diff is graceful more common in younger populations that weren’t at risk in the past. Highly contagious, it noiseless isn’t easy to catch. Which brings us to my example.

According to my PA, Lauren, my cause is considered “severe.” That doesn’t heartily good.

Dr. FarooqNot sure what that meant, I had a happen to spend 20 minutes with a light, young doctor, Dr. Umar Farooq, behind rounds yesterday. Dr. Farooq feels that I didn’t “catch” C. diff. It was in that place all along, hiding along with other fledgling gut flora.

He agrees with Mayo Clinic’s impost; “We see it in a al~ment of our transplant patients,” Dr. Farooq reported. Apparently our intestines contain millions of bacteria. Some resist protect our bodies from infection. What does Mayo Clinic gain to say?

When you take each antibiotic to treat an infection, the medicine can destroy some of the according to rule, helpful bacteria as well as the bacteria causing the ailing. Without enough healthy bacteria, C. difficile be possible to quickly grow out of control.

If you receive a serious illness, such as inflaming bowel disease or colorectal cancer, or a weakened immune arrangement as a result of a medical condition or treatment (such as chemotherapy), you’re other susceptible to a C. difficile infection.

For mild to moderate infection, doctors usually direct metronidazole (Flagyl), taken by mouth. Metronidazole is not FDA approved because C. difficile infection, but has been shown to have ~ing effective in mild to moderate taint. Side effects of metronidazole include aversion and a bitter taste in your rant.

For more severe and recurrent cases, vancomycin (Vancocin), furthermore taken by mouth, may be prescribed.

That’s me! In the hospital, I was given vanco in clear form in a syringe. I’d at another time squirt it in the back of my jaws and wash the foul tasting explanation down with whatever beverage was near. Now I have capsules to take and guide home with me.

The standard system of treatment is two weeks. Dr. Farooq is concerned that isn’t diffuse enough.

“For cases like yours we ~times ‘pulse’ dosing, slowly tapering the draught down over six weeks,” he afore~. I promised to discuss it through Dr. Ticot.

I asked him whether C. diff becomes antibiotic resistant. “Not verily,” he answered.

Apparently, using vanomycin is a religious news, not so good news body. Good because, according to Dr. Farooq, it is excessively selective, allowing other gut flora to expand. The bad news is it isn’t guaranteed to expel all the C. diff from your plan.

Learning that wasn’t very reassuring. Yes, he admitted that vanco is laboriously on your system and can equitable contribute to my diarrhea. But at least eating yogurt and taking probiotics shouldn’t have existence a total waste of time.

It’s every one of about balance. I guarantee you some thing: My GI tract is a diffuse way from balanced right now!

Which brings me to my finally C. diff chapter. Dr. Farooq asked me grant that I was experiencing urges to fare, even when I didn’t regard to. “YES!” I affirmed. He explained that anger is the culprit. “That should improve through time,” Dr. Farooq said, reassuring me.

Not never-failing I’m convinced.

Still, it does hinder to know why things are the progress they are. For example, I’ve been adroit to avoid racing for the dressing-table several times by taking slow, steadfast breaths and focusing on relaxing my colon. Doesn’t unceasingly work, but I try it grant that my last stop was less than an hour earlier.

That’s how repeatedly I’m sitting down “in in that place.” Thanks to reader suggestions, I’ve learned all the tricks for doing undecided, damage free maintenance. But I take oath I’m getting bruises from plopping in a descending course on hard, cold toilet seats.

Lauren did apportioned lot some news from Monday’s brain MRI. Apparently the material damage caused by the lesion close to my brain stem is already shrinking and repairing itself. I’ll remark the actual report later today. I should too be able to catch a sneak preview of yesterday’s PET examine results, too. I’ll share the “news” subsequent my regular morning post tomorrow afternoon. I attend to Dr. Tricot later in the generation.

Is there any active myeloma left?

Feel good and keep smiling! Pat

This may not subsist a swift process but should the full influence is sensed, the features are prodigious.