What follows is ~y exposition of Flagyl (Metronidazole) according to Chinese physic, and an analysis for treating its side effects, namely digestive discomfort and liver toxicity. This is apposite to transgender health care in that far-seeing-term medication use–for instance, of Spirolactone to keep secret androgens–may be associated with some degree of liver toxicity. Because Flagyl is incredibly hepatotoxic, any treatment of its side effects, especially those to the liver may subsist useful in palliative treatment of patients forward hormone-replacement therapy (HRT) for form relative to sex transition.
Metronidazole (MNZ), or Flagyl being of the kind which it is commonly known, is a nitroimidazole antibiotic and anti-wheedler medication, in this case used to feast amebiasis, such as E. histolytica. It works ~ dint of. inhibiting nucleic acid synthesis in the DNA of microbial cells.
Common indirect effects include nausea, diarrhea, abdominal unhappiness, headache, and dizziness. High doses and to a great extent-term treatment are associated with leucopenia, neutropenia, and central timid system toxicity. It is listed by the US National Toxicology Program to the degree that a reasonably anticipated human carcinogen, and ~ means of the WHO International Agency for Research in successi~ Cancer as a possible carcinogen.
From the vista of Chinese medicine, Flagyl is exceedingly cold in nature and bitter, like other antibiotics and antimicrobial herbs. As similar, taking it in large doses in excess a short period of time to handle parasites can be thought of of the same kind with excess cold invading the middle jiao, distinctly the ST. Likewise, the SP prefers to exist warm, and its qi will have existence damaged by a course of Flagyl. The SP is the rise of post-natal essence and is accountable for generating blood. If this discharge is damaged, there is less lineage available which will aggravate the LV. The LV means of communication is very testy, and as of the like kind requires a dynamic balance of passion/yin, and movement/yang. Any rent in this balance will lead to stagnation. In relationship to Flagyl, deficient SP qi owed to the invasion of excess cold could lead to less generation of LV descent and resultant qi stagnation. In a fashion, the LV then is both depleted and agitated simultaneously.
Hence, in the herbal formula from the previous post, sundry herbs that have an affinity ~ the sake of the LV are combined to return and maintain this yin-yang excess, namely Yin Chen (Herba Artemisiae Scorpariae), Bai Shao (Radix Paeoniae Alba), and Gou Qi Zi (Frustuc Lycii). This may take measures the basis for a general LV-sheltering protocol for countering the adverse movables of medication use.
Yin Chen has demonstrated hepatoprotective furniture, in that studies have shown that herbal formulas in which it is the first herb effectively reduce liver enzyme (ALT, AST) serum levels (1). Furthermore, Yin Chen has shown success in treating patients with acute contaminating hepatitis, reducing fever, jaundice, and overall liver sizing (2). The herb also has antihyperlipidemic qualities, and has been shown to diminish plasma cholesterols and beta-lipoproteins in rabbits (3). Though not listed in traditional herbal books as a function, these features be able to be thought of as cleaning the LV.
Bai Shao in Chinese sanatory theory is said to nourish the LV temper and preserve yin, calm LV yang, and regulate/soften the LV. These functions and through extension this herb are relevant to wholly potential LV disfunction, whether excess of insufficiency. In the case of a round of Flagyl, it can soften and unruffled the LV and likewise tonify some aspects of the LV that are inadequate. A thorough intake including tongue and pulse readings will determine the necessary quantities of Bai Shao and its apposite combinations with other herbs.
In pharmacological provisions, Bai Shao as been used to come to terms dysenteric disorders with rectal tenesmus. In other language, its qualities can treat any remaining symptoms from intestinal amebiasis such as occasional urgent diarrhea (4). It is also an anti-inflammatory and antibiotic, with inhibitory actions against Bacillus dysenteriae, E. Coli, Salmonella typhi, and others (5).
The last LV related herb in the rule is Gou Qi Zi, which nourishes LV yin. This herb has been shown to have existence immunostimulatory, and is associated with ~y increase in non-specific immunity so as phagocytic activity of macrophages and the mass number of T cells (6).
The synergistic compound of these herbs may form the lowest part of a LV balancing and hepatoprotective etc. to formulas for patients undergoing HRT and other drawn out-term medication use. Proportions and dosage being of the kind which always are determined by the patient’s predicament and the practitioner’s diagnosis steady that day.
Guo Wai Yi Xue Zong Yi Zhong Yao Fen, Monograph of Chinese Herbology from Foreign Medicine, 1986; 8(5):22.
Fu Jian Zhong Yi Yao, Fujian Chinese Medicine and Herbology, 1959; 7:42.
Zhong Yao Yao Li Yu Ying Yong, Pharmacology and Applications of Chinese Herbs,1990; 15(6): 52.
Xin Zhong Yi, New Chinese Medicine, 1989; 21(3): 51.
Zhong Yao Zhi, Chinese Herbology Journal, 1993: 183
Zhong Cao Yao, Chinese Herbal Medicine, 19(7):25.
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